Comments on: Supplements vs. Statins http://ageagainst.com/diet-and-exercise/supplements-vs-statins/ Fri, 17 Sep 2010 21:28:29 +0000 hourly 1 http://wordpress.org/?v=3.2.1 By: moddoctor http://ageagainst.com/diet-and-exercise/supplements-vs-statins/comment-page-1/#comment-431 moddoctor Sun, 20 Jul 2008 04:13:05 +0000 http://ageagainst.com/?p=42#comment-431 While true to a point, it's worth noting that the fraction of active compounds in Red Yeast Rice that is chemically identical (monacolin K) is minute, 2.53mg in each dose in the study. Compate this to 20mg of the commercial product Mevacor as a typical starting dose. So, either there is a synergistic effect of providing the surrounding monacolin compounds or the fish oil or both. Use of HMG-CoA reductase type compounds like monacolin K/lovastatin carries with it significant biological liabilities such as inhibition of synthesis of Co-Enzyme Q10. Even if clinically we end up merely using very low dose statins with fish oil, not inhibiting the other legs of the chemical sequences involved (like Q10 synthesis) I think the patient comes out ahead. While true to a point, it’s worth noting that the fraction of active compounds in Red Yeast Rice that is chemically identical (monacolin K) is minute, 2.53mg in each dose in the study. Compate this to 20mg of the commercial product Mevacor as a typical starting dose. So, either there is a synergistic effect of providing the surrounding monacolin compounds or the fish oil or both.

Use of HMG-CoA reductase type compounds like monacolin K/lovastatin carries with it significant biological liabilities such as inhibition of synthesis of Co-Enzyme Q10. Even if clinically we end up merely using very low dose statins with fish oil, not inhibiting the other legs of the chemical sequences involved (like Q10 synthesis) I think the patient comes out ahead.

]]> By: John C. Campbell III http://ageagainst.com/diet-and-exercise/supplements-vs-statins/comment-page-1/#comment-430 John C. Campbell III Sat, 19 Jul 2008 21:19:07 +0000 http://ageagainst.com/?p=42#comment-430 Summarily, the base active agent in "manufactured" statin prescriptions ... (lovastin) ... is the same that is the active compound (a toxin) in Red Rice Yeast ... Google for "SpaceDoc" and look at Dr. Duane Graveline's site for starters ... jccampb Summarily, the base active agent in “manufactured” statin prescriptions … (lovastin) … is the same that is the active compound (a toxin) in Red Rice Yeast … Google for “SpaceDoc” and look at Dr. Duane Graveline’s site for starters …
jccampb

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